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Telomerase Inhibitor IX-CAS 368449-04-1-Calbiochem
| 产品编号： | 4151727 |
| 规格： | The Telomerase Inhibitor IX, also referenced under CAS 368449-04-1, controls the biological activity of Telomerase. This small molecule/inhibitor is primarily used for Cell Structure applications. |
| CAS NO： | 368449-04-1 |
| 包装规格： | 10 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4151727 | 10 MG | 2510 | 2-5天 | 4-6周 |
产品别名
368449-04-1
Telomerase Inhibitor IX-CAS 368449-04-1-Calbiochem
MST-312, N,N'-bis(2,3-Dihydroxybenzoyl)-1,3-phenylenediamine
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H16N2O6 |
| Molecular weight | 380.35 |
| MDL number | MFCD24368986 |
| General description【一般描述】 | A cell-permeable, bis-catechol containing, m-phenylenediamide compound that displays anti-proliferative properties. Acts as a potent, reversible inhibitor of telomerase activity (IC50 = 670 nM, TRAP lysate prepared from U937 cells). Prolonged treatment with MST-312 has been reported to result in telomere shortening and growth arrest in U937 cells. Does not inhibit the activity of Taq DNA polymerase (IC50 >3 µM). |
| Biochem/physiol Actions【生化/生理作用】 | Cell permeable: yes Target IC50: 670 nM against telomerase activity in TRAP lysate prepared from U937 cells Product does not compete with ATP. Primary Target TRAP lysate prepared from U937 cells Reversible: yes |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Reconstitution【重悬】 | Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. |
| Other Notes【其他说明】 | Seimiya, H., et al. 2005. Cancer Cell7, 25. Seimiya, H., et al. 2002. Mol. Cancer Ther.1, 657. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze protect from light |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: 5 mg/mL |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 10 mg in Plastic ampoule Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 2 |
