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MnTMPyP-Calbiochem
| 产品编号： | 4152406 |
| 规格： | Cell-permeable superoxide dismutase (SOD) mimetic. |
| 包装规格： | 25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
MnTMPyP-Calbiochem
Mn(III)tetrakis(1-methyl-4-pyridyl)porphyrin, Tetratosylate, Hydroxide
基本信息
| Empirical Formula【经验(实验)分子式】 | C72H65MnN8O13S4 |
| Molecular weight | 1433.53 |
| General description【一般描述】 | Cell-permeable superoxide dismutase (SOD) mimetic. Catalyzes the dismutation of O2– • (rate constant ~4 x 107 M-1 s-1) even in the presence of excess EDTA. Can substitute for SOD in mutants of E. coli lacking this enzyme. MnTMPyP acts in vivo as an NADPH/GSH:O2• oxidoreductase rather than as an SOD mimetic. Also an efficient peroxynitrite reductase when redox-coupled with biological antioxidants. |
| Biochem/physiol Actions【生化/生理作用】 | Cell permeable: yes Product does not compete with ATP. Reversible: no |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Other Notes【其他说明】 | Izbicka, E., et al. 1999. Cancer Res.59, 639. Lee, J., et al. 1998. J. Am. Chem. Soc. 120, 6053. Gardner, P.R., et al. 1996. Arch. Biochem. Biophys. 325, 20. Liochev, S.I., and Fridovich, I. 1995. Arch. Biochem. Biophys. 321, 271. Faulkner, K.M., et al. 1994. J. Biol. Chem. 269, 23471. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (TLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated protect from light |
| color【颜色】 | black |
| solubility【溶解性】 | water: 1 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 25 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
