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2-Chloro-2'-deoxyadenosine-CAS 4291-63-8-Calbiochem
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4153010 | 10 MG | 964 |
产品别名
4291-63-8
2-Chloro-2'-deoxyadenosine-CAS 4291-63-8-Calbiochem
2CdA, Cladribine
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H12ClN5O3 |
| Molecular weight | 285.69 |
| MDL number | MFCD00153939 |
| General description【一般描述】 | A deoxyadenosine analog that displays strong antileukemic and immunosuppressive activity. Also induces apoptosis in chronic lymphocytic leukemia (CLL) cells. |
| Biochem/physiol Actions【生化/生理作用】 | Product does not compete with ATP. Reversible: no Cell permeable: no Primary Target Antileukemic and immunosuppressive activity |
| Warning【警告】 | Toxicity: Harmful & Carcinogenic / Teratogenic (E) |
| Other Notes【其他说明】 | Bellosillo, B., et al. 1997. Blood 89, 3378; Bryson, H.M., and Sorkin, E.M. 1993. Drugs 46, 872. Robertson, L.E., et al. 1993. Blood81, 143. Carson, D.A., et al. 1988. Adv. Enzyme Regul. 27, 395. Carson, D.A., et al. 1984. Proc. Natl. Acad. Sci. USA 81, 2232. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: 5 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| InChI | 1S/C10H12ClN5O3/c11-10-14-8(12)7-9(15-10)16(3-13-7)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H2,12,14,15)/t4-,5+,6+/m0/s1 |
| InChI key | PTOAARAWEBMLNO-KVQBGUIXSA-N |
| packaging【包装】 | 10 mg in Plastic ampoule |
安全信息
| Pictograms【象形图】 | GHS06,GHS08 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 - H341 - H361fd - H372 |
| Precautionary Statements | P201 - P202 - P260 - P264 - P270 - P301 + P310 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral - Muta. 2 - Repr. 2 - STOT RE 1 |
| Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
