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Anti-COMP (Thrombospondin-5) Antibody, clone 484D1
产品别名
Anti-COMP (Thrombospondin-5) Antibody, clone 484D1
Cartilage oligomeric matrix protein, Thrombospondin-5
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Cartilage oligomeric matrix protein (COMP, Thrombospondin-5, TSP5) is a member of the thrombospondin gene family. COMP is usually found in the extracellular matrix and is regularly linked to cartilage tissue. COMP seems to protect chondrocytes against cell death, whether tumor necrosis factor alpha is present or not. Defects in COMP are the cause of multiple epiphyseal dysplasia type 1 and pseudoachondroplasia. |
| Immunogen【免疫原】 | Human cartilage oligometric matrix recombinant protein. |
| Application【应用】 | Research Category Cell Structure This Anti-COMP (Thrombospondin-5) Antibody, clone 484D1 is validated for use in WB, IH for the detection of COMP (Thrombospondin-5). Immunohistochemistry (Frozen Tissue) Analysis: A previous lot of this antibody was shown to detect COMP in osteoblasts lining the bone spicules of adult human subchondral bone section (Di Cesare, P.E., et al. (2000). Journal of Orthopaedic Research. 18:713.720). Research Sub Category ECM Proteins |
| Quality【质量】 | Evaluated by Western Blot in human chrondrocytes cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected COMP in 10 µg of human chrondrocyte cell lysate. |
| Physical form【外形】 | Format: Purified Purified rat monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Protein G Purified |
| Analysis Note【分析说明】 | Control Human chrondrocyte cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | rat |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 484D1, monoclonal |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_000086 |
| UniProt accession no.【UniProt登记号】 | P49747 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~83 kDa Observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
