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产品别名
Anti-DAP-5 Antibody
Death-associated protein 5, aging-associated protein 1, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, eukaryotic translation initiation factor 4 gamma, 2, eukaryotic translation initiation factor 4G-like 1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Death Associated Protein 5 (DAP-5) is a protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. DAP5 is cleaved at Asp790 during apoptosis . The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis. |
| Specificity【特异性】 | This antibody recognizes DAP-5. |
| Immunogen【免疫原】 | Epitope: Unknown KLH-conjugated linear peptide corresponding to human DAP-5. |
| Application【应用】 | Research Sub Category Apoptosis - Additional Research Category Apoptosis & Cancer This Anti-DAP-5 Antibody is validated for use in WB for the detection of DAP-5. |
| Quality【质量】 | Evaluated by Western Blot on Jurkat cell lysate. Western Blot Analysis: 1:1,000 dilution of this antibody detected DAP-5 on 10 µg of jurkat cell lysate. |
| Physical form【外形】 | Unpurified Rabbit polyclonal serum containing 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control Jurkat cell lysate |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | serum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | mouse, human |
| species reactivity (predicted by homology) | rat (based on 100% sequence homology) |
| technique(s) | western blot: suitable |
| isotype【同位素/亚型】 | IgG |
| NCBI accession no.【NCBI登记号】 | NP_001036024.1 |
| UniProt accession no.【UniProt登记号】 | P78344 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... EIF4G2(1982) |
产品说明
| Target description【目标描述】 | 97 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at -20°C from date of receipt. Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
