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Anti-HLA-DRB1 Antibody, clone DJ9
产品别名
Anti-HLA-DRB1 Antibody, clone DJ9
Major histocompatibility complex, class II, DRB1, DRB1
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. HLA-DRB1 binds peptides derived from antigens that access the endocytic route of antigen presenting cells and presents them on the cell surface for recognition by the CD4 T-cells. Class II molecules are expressed in antigen presenting cells B lymphocytes, dendritic cells, macrophages. HLA-Drb1 is expressed at a level five times higher than its paralogs DRB3, DRB4 and DRB5. HLA-DRB1, clone DJ9, has been shown to be a relevant marker of bone marrow derived mesenchymal stem cells and their osteogenic derivatives (Andersen, D., et al., 2011). |
| Specificity【特异性】 | This antibody recognizes human HLA-DRB1. |
| Immunogen【免疫原】 | Whole hMSC-TERT Cells |
| Application【应用】 | Research Category Inflammation & Immunology Stem Cell Research This antibody has been shown to work in Immunocytochemistry (Andersen, D., et al. (2011)). This antibody has been shown to work in Immunohistochemistry (Andersen, D., et al. (2011)). This antibody has been shown to work in Flow Cytometry (Andersen, D., et al. (2011)). Detect HLA-DRB1 using this Anti-HLA-DRB1 Antibody, clone DJ9 validated for use in Western Blotting, ICC, IHC, Flow Cytometry. Research Sub Category Immunological Signaling Mesenchymal Stem Cells |
| Quality【质量】 | Evaluated by Western Blot in Daudi cell lysates. Western Blot Analysis: A 1:100,000 dilution of this antibody detected HLA-DRB1 in Duadi cell lysates. |
| Physical form【外形】 | Format: Purified Protein G Purified |
| Analysis Note【分析说明】 | Control Daudi cell lysates |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | DJ9, monoclonal |
| species reactivity | human |
| technique(s) | flow cytometry: suitable immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_002112 |
| UniProt accession no.【UniProt登记号】 | Q5Y7A7 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... HLA-DRB1(3123) |
产品说明
| Target description【目标描述】 | ~30 kDa observed |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
