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Anti-Integrin beta-2 (CD18) Antibody, clone M18/2
产品别名
Anti-Integrin beta-2 (CD18) Antibody, clone M18/2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), integrin beta chain, beta 2, complement receptor C3 beta-subunit, leukocyte cell adhesion molecule CD18, integrin beta-2, Complement receptor C3 subunit beta, Cell surface adhesion glyco
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Integrin beta-2, also known as CD18, is an adhesion receptor in neutrophils that interacts with cytohesin-1 intracellularly. Integrin beta is instrumental in activation-dependent adhesion and adhesion-dependent signaling. Expression of integrin beta-2 has a positive correlation with patient survival from malignant B cell lymphoma. |
| Immunogen【免疫原】 | Whole B10 mouse spleen cells enriched with T-cells. |
| Application【应用】 | Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP (Sanchez-Madrid, F., et al. (1983). J. ExP. MED. 158:586-602). Inhibition Analysis: A previous lot of this antibody was shown to inhibit lymphoma metastasis (Zahalka, M. A. et al. (1993) J. Immunol. 150, 4466). This Anti-Integrin beta-2 (CD18) Antibody, clone M18/2 is validated for use in FC, IP for the detection of Integrin beta-2 (CD18). |
| Quality【质量】 | Evaluated by Flow Cytometry in mouse EL4 cells. Flow Cytometry Analysis: 10 µg of this antibody detected Integrin beta-2 in mouse EL4 cells. |
| Physical form【外形】 | Protein G Purified Format: Purified |
| Analysis Note【分析说明】 | Control Mouse EL4 cells |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | rat |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | M18/2, monoclonal |
| species reactivity | mouse |
| technique(s) | flow cytometry: suitable immunoprecipitation (IP): suitable |
| isotype【同位素/亚型】 | IgG2aκ |
| NCBI accession no.【NCBI登记号】 | NP_032430 |
| UniProt accession no.【UniProt登记号】 | P11835 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 85 kDa calculated |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
