您的位置：首页 > 产品中心 > Anti-ISL-1 Antibody
Anti-ISL-1 Antibody
| 产品编号： | 4154541 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-ISL-1 Antibody
ISL LIM homeobox 1, ISL1 transcription factor, LIM/homeodomain, ISL1 transcription factor, LIM/homeodomain, (islet-1)
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Islet-1 (ISL-1) is a transcription factor that plays an important role in the embryogenesis of pancreatic islets of Langerhans. It is expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain. In mouse embryos, a deficiency of this gene fail to undergo neural tube motor neuron differentiation. More recently it has been identified as a marker for a cardiac progenitor cell lineage that is capable of differentiating into all 3 major heart cell types: cardiomyocytes, smooth muscle and endothelial cell lineages. |
| Specificity【特异性】 | Predicted to react with most common vertebrate species based on 100% sequence homology. This antibody recognizes ISL-1. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human ISL-1. Epitope: Internal region of ISL-1. |
| Application【应用】 | Immunohistochemistry Analysis: A 1:300 dilution from a previous lot detected ISL-1 in mouse pancreas tissue. Anti-ISL-1 Antibody is a Rabbit Polyclonal Antibody for detection of ISL-1 also known as ISL LIM homeobox 1, ISL1 transcription factor LIM/homeodomain & has been validated in WB & IHC. |
| Quality【质量】 | Evaluated by Western Blot in K562 cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected ISL-1 on 10 µg of K562 cell lysate. |
| Other Notes【其他说明】 | Affinity purified |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human, horse, mouse |
| species reactivity (predicted by homology) | bovine (based on 100% sequence homology), rat (based on 100% sequence homology), canine (based on 100% sequence homology), equine (based on 100% sequence homology), sheep (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_002193 |
| UniProt accession no.【UniProt登记号】 | P61371 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... ISL1(3670) |
产品说明
| Target description【目标描述】 | ~39 kDa |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
