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Anti-Laminin alpha 5 Antibody, clone 4B12
产品别名
Anti-Laminin alpha 5 Antibody, clone 4B12
laminin, alpha 5, Laminin-15 subunit alpha, laminin alpha-5 chain, Laminin-11 subunit alpha, laminin subunit alpha-5, Laminin-10 subunit alpha, Laminin α5, Lamininα5, Laminin-α5
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Laminin alpha 5 (α5) is a member of the laminin family of extracellular matrix glycoproteins. Laminin’s are important in cell migration, differentiation and in tumor cell incursion. Research shows that laminin alpha 5 may be an early marker of sexual differentiation. In rat, the laminin alpha 5 chain seems to halt expression in the basement membrane of Sertoli cells when secretion of AMH begins but expression increases two weeks after birth when AMH secretion stops. Laminin alpha 5 shows up early during lung development in mice. It has also been linked to inflammatory cell chemotaxis and metalloproteinase activity and may play a role in creating and sustaining mucosal patterns of the mouse small intestine. |
| Immunogen【免疫原】 | Laminin purified from human placenta |
| Application【应用】 | Research Category Cell Structure Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected Laminin alpha 5 in human blood vessels and metastatic colorectal adenocarcinoma tissues. This Anti-Laminin alpha 5 Antibody, clone 4B12 is validated for use in IH for the detection of Laminin alpha 5. Research Sub Category ECM Proteins |
| Quality【质量】 | Evaluated by Immunohistochemistry in human precancerous colorectal lesion tissue. Immunohistochemistry Analysis: A 1:100 dilution of this antibody detected Laminin alpha 5 in human precancerous colorectal lesion tissue. |
| Physical form【外形】 | Format: Purified Protein G Purified Purified mouse monoclonal IgG1λ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control Human precancerous colorectal lesion tissue |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | 4B12, monoclonal |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable |
| isotype【同位素/亚型】 | IgG1λ |
| NCBI accession no.【NCBI登记号】 | NP_005551 |
| UniProt accession no.【UniProt登记号】 | O15230 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | 400 kDa calculated |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
