您的位置：首页 > 产品中心 > Anti-MEF2D Antibody
Anti-MEF2D Antibody
| 产品编号： | 4154601 |
| 规格： | from rabbit, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-MEF2D Antibody
myocyte enhancer factor 2D, MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D), MEF2D/DAZAP1 fusion, myocyte-specific enhancer factor 2D, myocyte enhancer factor 2D/deleted in azoospermia associated protein 1 fusion prot
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Myocyte-specific enhancer factor 2D is a transcriptional activator belonging to the MEF2 family. MEF2D has two domains of interest; a MADS-box domain, and a Mef2-type DNA-binding domain specifically binding to 5′-YTA[AT]4TAR-3′, the MEF2 element, which is observed in several gene types such as growth factor, muscle-specific, and stress-induced genes. MEF2D regulates various cellular processes including those within cardiac and skeletal muscle development, neuronal survival and differentiation, as well as cell growth, apoptosis and survival. MEF2D, along with ERK5, plays a vital role in neuronal survival by regulating the anti-apoptotic molecule, bcl-w. There are 6 known isoforms of MEF2D resulting from alternative splicing. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to human MEF2D. |
| Application【应用】 | Anti-MEF2D Antibody is an antibody against MEF2D for use in WB, IH(P). Immunohistochemistry Analysis: 1:300 dilution from a previous lot detected MEF2D in normal human breast skin and inflammatory skin tissue. Research Category Neuroscience Research Sub Category Neurodegenerative Diseases |
| Quality【质量】 | Evaluated by Western Blot in L6 cell lysate. Western Blot Analysis: 0.5 µg/mL of this antibody detected MEF2D on 10 µg of L6 cell lysate. |
| Physical form【外形】 | Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Affinity purified |
| Analysis Note【分析说明】 | Control L6 cell lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | horse, pig, human, rhesus macaque, mouse, rat |
| species reactivity (predicted by homology) | porcine (based on 100% sequence homology), equine (based on 100% sequence homology), canine (based on 100% sequence homology), rhesus monkey (based on 100% sequence homology) |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NP_005911 |
| UniProt accession no.【UniProt登记号】 | Q14814 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... MEF2D(4209) |
产品说明
| Target description【目标描述】 | Observed at ~ 54 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
