您的位置：首页 > 产品中心 > Anti-mouse CD44 (H-CAM) Antibody, clone KM201
Anti-mouse CD44 (H-CAM) Antibody, clone KM201
产品别名
Anti-mouse CD44 (H-CAM) Antibody, clone KM201
CD44 antigen (homing function and Indian blood group system), CDw44 antigen, HCAM, H-CAM, HUTCH-1, Phagocytic glycoprotein I, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, Heparan sulfate proteoglycan, Hermes antigen, Hyalu
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | CD44, also known as H-CAM is a distinct adhesion molecule that, with its 13 known isoforms, comprises a family of transmembrane glycoproteins involved in a wide variety of significant biological processes. Members belonging to this family are involved in apoptosis, migration, metastasis, tumor progression, lymphocyte homing, and the attachment of hematopoietic cells to stromal cells. CD44 is the primary cell surface receptor for hyaluronic acid (HA), and is also a notable target for WNT signaling within the intestinal mucosa. Recent studies have used CD44 marker as a means to isolate different cancer stem cells (CSC) such as; colorectal CSC, pancreatic CSC, and prostate CSC. |
| Specificity【特异性】 | The antibody recognizes CD44 near the hyaluronate binding domain. |
| Immunogen【免疫原】 | Mouse bone marrow-derived stromal cells Epitope: Near the hyaluronate binding domain |
| Application【应用】 | Research Sub Category Adhesion (CAMs) Hematopoietic Stem Cells Research Category Cell Structure Stem Cell Research Detect mouse CD44 (H-CAM) using this Anti-mouse CD44 (H-CAM) Antibody, clone KM201 validated for use in FC. |
| Quality【质量】 | Evaluated by Flow Cytometry in mouse bone marrow cells. Flow Cytometry Analysis: 0.1 µg of this antibody detected CD44 in mouse bone marrow cells. |
| Linkage【联系】 | Replaces: CBL1308 |
| Physical form【外形】 | Format: Purified Purified rat monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine, pH 7.4, 150 mM NaCl, with 0.05% sodium azide. Protein G |
| Analysis Note【分析说明】 | Control Mouse bone marrow cells |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | rat |
| antibody form【抗体形式】 | purified antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | KM201, monoclonal |
| species reactivity | mouse |
| technique(s) | flow cytometry: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_001034240 |
| UniProt accession no.【UniProt登记号】 | P15379 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... CD44(960) |
产品说明
| Target description【目标描述】 | 86 kDa calculated |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
