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Anti-MyT1L Antibody, clone 20B4.1
产品别名
Anti-MyT1L Antibody, clone 20B4.1
Myelin transcription factor 1-like protein, MyT1-L, MyT1L
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Myelin transcription factor 1-like (Myt1L) is a zinc finger protein belonging to the myelin transcription factor 1 family. It influences the expression of genes involved in the proliferation and differentiation of oligodentrocytes in the developing central nervous system. Myt1L may contribute to the silencing of its target genes by recruiting Sin3B that binds to and enhances the activity of HDAC. Several studies have implicated Myt1L in the pathogenesis of complex psychiatric diseases such as schizophrenia, major depressive disorder, and bipolar disorder. |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to human MyT1L. |
| Application【应用】 | Detect the MyT1L protein using this Anti-MyT1L, clone 20B4.1 validated for use in WB & IHC. Immunohistochemistry Analysis: A 1:10-1:50 dilution from a representative lot detected MyT1L in human pons, mouse frontal cortex, and mouse hippocampus tissues. Research Category Neuroscience Research Sub Category Developmental Neuroscience |
| Quality【质量】 | Evaluated by Western Blot in mouse E17 spinal cord tissue lysate. Western Blot Analysis: A 1:1.000 dilution of this antibody detected MyT1L on 10 µg of mouse E17 spinal cord tissue lysate. |
| Physical form【外形】 | Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. Format: Purified Protein G Purified |
| Analysis Note【分析说明】 | Control Mouse E17 spinal cord tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 20B4.1, monoclonal |
| species reactivity | mouse, human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_055840 |
| UniProt accession no.【UniProt登记号】 | Q9UL68 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... MYT1L(23040) |
产品说明
| Target description【目标描述】 | ~170 kDa observed. Uniprot describes three isoforms at 21, 126, and 133 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
