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Anti-PINK1 Antibody, clone N4/49
产品别名
Anti-PINK1 Antibody, clone N4/49
PTEN induced putative kinase 1, protein kinase BRPK, serine/threonine-protein kinase PINK1, PTEN-induced putative kinase protein 1, Parkinson disease (autosomal recessive) 6
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Mutations in the PTEN-induced kinase 1 (PINK1) gene located within the PARK6 locus on chromosome 1p35-p36 have recently been identified in patients with recessive early-onset Parkinson disease. Data suggests that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. |
| Specificity【特异性】 | This antibody recognizes PINK1. |
| Application【应用】 | This Anti-PINK1 Antibody, clone N4/49 is validated for use in IH, WB for the detection of PINK1. Western Blot Analysis: A previous lot of MABN18 recognized PINK1 in HEK cells and a rat brain LSP, as reported by an independent laboratory (UC Davis/NIH NeuroMab Facility; www.neuromab.org/neuromab@ucdavis.edu). |
| Quality【质量】 | Evaluated by Immunohistochemistry in human normal brain tissue. Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected PINK1 in human normal brain tissue. |
| Physical form【外形】 | Protein G Purified Format: Purified |
| Analysis Note【分析说明】 | Control Human normal brain tissue |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | N4/49, monoclonal |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG1κ |
| NCBI accession no.【NCBI登记号】 | NP_115785 |
| UniProt accession no.【UniProt登记号】 | Q9BXM7 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... PINK1(65018) |
产品说明
| Target description【目标描述】 | 63 kDa Observed |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
