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Anti-Slo1 Antibody, clone L6/60
产品别名
Anti-Slo1 Antibody, clone L6/60
potassium large conductance calcium-activated channel, subfamily M, alpha member 1, Slo homolog, stretch-activated Kca channel, Maxi K channel, Drosophila slowpoke-like, Calcium-activated potassium channel, subfamily M subunit alpha-1, Slowpoke homolog,
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Slo1 (Calcium-activated potassium channel subunit alpha-1) may not only be activated by membrane depolarization but may also be by an increase in cytosolic Ca2+. The concentration of cytosolic Mg2+ also activates this potassium channel. Found to play a part in the repolarization of the membrane potential due to the fact that it diminishes the excitatory voltage in the cell. |
| Specificity【特异性】 | This antibody recognizes S9-S10 segments of Slo1. |
| Immunogen【免疫原】 | Recombinant protein corresponding to the S9-S10 segments of mouse Slo1. Epitope: S9-S10 segments |
| Application【应用】 | Detect Slo1 using this Anti-Slo1 Antibody, clone L6/60 validated for use in IH, WB & IC. Immunohistochemistry Analysis: 1:500 dilution from a previous lot detected Slo1 in rat cerebellum tissue. Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC. (Misonou, H., et al. (2006). J Comp Neurol. 496(3):289–302.) Research Sub Category Signaling Neuroscience Research Category Neuroscience |
| Quality【质量】 | Evaluated by Western Blot in rat brain membrane tissue lysate. Western Blot Analysis: 1 µg/mL of this antibody detected Slo1 on 10 µg of rat brain membrane tissue lysate. |
| Physical form【外形】 | Format: Purified Protein G Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control Rat brain membrane tissue lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | L6/60, monoclonal |
| species reactivity | rat |
| species reactivity (predicted by homology) | mouse (immunogen homology) |
| technique(s) | immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgG2aκ |
| NCBI accession no.【NCBI登记号】 | NP_034740 |
| UniProt accession no.【UniProt登记号】 | Q08460 |
| shipped in【运输】 | wet ice |
| Gene Information | human ... KCNMA1(3778) |
产品说明
| Target description【目标描述】 | ~100 kDa observed |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
