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Anti-Slo1 Antibody, clone L6/60

产品编号:4154935
规格:clone L6/60, from mouse
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4154935100 μG6350
产品别名

Anti-Slo1 Antibody, clone L6/60

potassium large conductance calcium-activated channel, subfamily M, alpha member 1, Slo homolog, stretch-activated Kca channel, Maxi K channel, Drosophila slowpoke-like, Calcium-activated potassium channel, subfamily M subunit alpha-1, Slowpoke homolog,

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
Slo1 (Calcium-activated potassium channel subunit alpha-1) may not only be activated by membrane depolarization but may also be by an increase in cytosolic Ca2+. The concentration of cytosolic Mg2+ also activates this potassium channel. Found to play a part in the repolarization of the membrane potential due to the fact that it diminishes the excitatory voltage in the cell.
Specificity【特异性】
This antibody recognizes S9-S10 segments of Slo1.
Immunogen【免疫原】
Recombinant protein corresponding to the S9-S10 segments of mouse Slo1.
Epitope: S9-S10 segments
Application【应用】
Detect Slo1 using this Anti-Slo1 Antibody, clone L6/60 validated for use in IH, WB & IC.
Immunohistochemistry Analysis: 1:500 dilution from a previous lot detected Slo1 in rat cerebellum tissue.

Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC. (Misonou, H., et al. (2006). J Comp Neurol. 496(3):289–302.)
Research Sub Category
Signaling Neuroscience
Research Category
Neuroscience
Quality【质量】
Evaluated by Western Blot in rat brain membrane tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected Slo1 on 10 µg of rat brain membrane tissue lysate.
Physical form【外形】
Format: Purified
Protein G
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Analysis Note【分析说明】
Control
Rat brain membrane tissue lysate
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
L6/60, monoclonal
species reactivity
rat
species reactivity (predicted by homology)
mouse (immunogen homology)
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
isotype【同位素/亚型】
IgG2aκ
NCBI accession no.【NCBI登记号】
NP_034740
UniProt accession no.【UniProt登记号】
Q08460
shipped in【运输】
wet ice
Gene Information
human ... KCNMA1(3778)
产品说明
Target description【目标描述】
~100 kDa observed
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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