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Anti-S1PR2/EDG5 Antibody, clone 6E8.1
产品别名
Anti-S1PR2/EDG5 Antibody, clone 6E8.1
Sphingosine 1-phosphate receptor 2, S1P receptor 2, S1P2, Endothelial differentiation G-protein coupled receptor 5, Sphingosine 1-phosphate receptor Edg-5, S1P receptor Edg-5
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Sphingosine 1-phosphate receptor 2 (S1PR2), otherwise known as EDG5, is a ubiquitous G-protein coupled receptor for lysosphingolipid sphingosine 1-phosphate (S1P). It is coupled to Gi, G12/13, and Gq pathways to regulate a number of second messengers and effector molecules, including cAMP, PLC, MAPK, RhoA, and Rac. S1PR2 mediates the effects of S1P on cell motility and embryonic development, among other cellular processes. |
| Specificity【特异性】 | This antibody recognizes the cytoplasmic domain of S1PR2/EDG5. |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to the cytoplasmic domain of human S1PR2/EDG5. |
| Application【应用】 | Immunohistochemistry Analysis: A representative lot detected S1PR2/EDG5 in human tonsil, liver, colorectal cancer tissues. Anti-S1PR2/EDG5 Antibody, clone 6E8.1 detects level of S1PR2/EDG5 & has been published & validated for use in Western Blotting, IHC(P). |
| Quality【质量】 | Evaluated by Western Blot in human liver tissue lysate. Western Blot Analysis: 1 µg/mL of this antibody detected S1PR2/EDG5 in 10 mg of human liver tissue lysate. |
| Physical form【外形】 | Purified by Ion-Exchange Chromatography Format: Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 6E8.1, monoclonal |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable (paraffin) western blot: suitable |
| isotype【同位素/亚型】 | IgMκ |
| NCBI accession no.【NCBI登记号】 | NP_004221 |
| UniProt accession no.【UniProt登记号】 | O95136 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~35 kDa observed |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
