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Anti-S1PR4/EDG6 Antibody, clone 16B9.1
产品别名
Anti-S1PR4/EDG6 Antibody, clone 16B9.1
Sphingosine 1-phosphate receptor 4, S1P receptor 4, S1P4, Endothelial differentiation G-protein coupled receptor 6, Sphingosine 1-phosphate receptor Edg-6, S1P receptor Edg-6
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Sphingosine 1-phosphate receptor 4 (S1PR4), otherwise known as EDG6, is present, in varying expression levels, in the adult lymph node, bone marrow, and thymus, as well as fetal liver, lung, and thymus. It is activated by the lysosphingolipid sphingosine 1-phosphate, and is coupled to Gi and G12/13 G proteins and via their various effector molecules, SIP4 regulates cell proliferation, differentiation, motility, and migration. |
| Immunogen【免疫原】 | GST-tagged recombinant protein corresponding to human S1PR4/EDG6. |
| Application【应用】 | Detect S1PR4/EDG6 using this Anti-S1PR4/EDG6 Antibody, clone 16B9.1 validated for use in Western Blotting & IHC. Immunohistochemistry Analysis: A 1:300 dilution from a representative lot detected S1PR4/EDG6 in human red bone marrow and human tonsil tissues. |
| Quality【质量】 | Evaluated by Western Blot Analysis in rat spleen tissue lysate. Western Blot Analysis: 1 µg/mL of this antibody detected S1PR4/EDG6 in 10 µg of rat spleen tissue lysate. |
| Physical form【外形】 | Purified by Ion-Exchange Chromatography Format: Purified |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 16B9.1, monoclonal |
| species reactivity | human, rat |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgMκ |
| NCBI accession no.【NCBI登记号】 | NP_003766 |
| UniProt accession no.【UniProt登记号】 | O95977 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~42 kDa observed |
| 【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 2 |
