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Anti-Tbr2 Antibody
| 产品编号： | 4154999 |
| 规格： | from chicken, purified by affinity chromatography |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Tbr2 Antibody
Eomesodermin homolog, T-box brain protein 2, T-brain-2, TBR-2, Tbr2
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Eomesodermin homolog (UniProt O54839; also known as T-box brain protein 2, T-brain-2, TBR-2) is encoded by the Eomes (also known as Tbr2, C77258) gene (Gene ID 13813) in murine species. Tbr2 is a member of a conserved protein family that shares a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Trb2 has been shown to play a role in the development of the neocortex and functions in the differentiation pathway of radial glia to post-mitotic projection neuron. |
| Specificity【特异性】 | Expected to react with both spliced isoforms of murine Tbr2. |
| Immunogen【免疫原】 | KLH-conjugated linear peptide corresponding to mouse Tbr2. Epitope: Transcription Activation Domain |
| Application【应用】 | This Anti-Tbr2 antibody is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of Tbr2. Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected Tbr2 in mouse cerebral cortex and mouse cerebellum tissue. Western Blot (SNAP ID) Analysis: 0.5 µg/ml from a previous lot detected Tbr2 in 10 µg of E13-14 mouse brain lysate. Immunohistochemistry Analysis: 1:100 dilution from a previous lot detected Tbr2 in mouse and human brain. Research Category Neuroscience Research Sub Category Developmental Neuroscience |
| Quality【质量】 | Evaluated by Western Blot in E13-14 mouse brain lysate. Western Blot Analysis: 0.05 µg/ml of this antibody detected Tbr2 in 10 µg of E13-14 mouse brain lysate. |
| Physical form【外形】 | Affinity purified Purified chicken polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. |
| Analysis Note【分析说明】 | Control E13-14 mouse brain lysate |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | chicken |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| purified by【纯化方式】 | affinity chromatography |
| species reactivity | human, mouse, rat |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| isotype【同位素/亚型】 | IgY |
| NCBI accession no.【NCBI登记号】 | NP_034266 |
| UniProt accession no.【UniProt登记号】 | O54839 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | ~85/95 kDa observed. Target bands appear larger than the calculated molecular size of 74.8 kDa (isoform 1) and 72.7 kDa (isoform 2). |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8°C from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
