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Anti-TNRC6B Antibody

产品编号:4155030
规格:from rabbit, purified by affinity chromatography
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4155030100 μG5350
产品别名

Anti-TNRC6B Antibody

Trinucleotide repeat-containing gene 6B protein

基本信息
eCl@ss
32160702
NACRES
NA.41
General description【一般描述】
TNRC6B (trinucleotide repeat containing 6B) is a argonaute-associated protein that localizes to cytoplasmic P bodies and is essential for control of miRNA-guided mRNA cleavage. TNRC6B is one of the mammalian homologs of the metazoan GW182 and is required for well-organized miRNA repression. Studies suggest that TNRC6B-mediated miRNA silencing is promoted by the C-terminal silencing domain.
Specificity【特异性】
Antibody recognizes TNRC6B
Immunogen【免疫原】
Epitope: N-terminan domain of TNRC6B
KLH-conjugated linear peptide corresponding to human TNRC6B.
Application【应用】
Anti-TNRC6B Antibody is a Rabbit Polyclonal Antibody for detection of TNRC6B also known as Trinucleotide repeat-containing gene 6B protein & has been validated in WB, ICC & IP.
Research Category
Epigenetics & Nuclear Function
Immunocytochemistry Analysis: 1:500 dilution from a representative lot detected TNRC6B in HeLa cells. (Zipprich, J., et al. (2009). RNA. 15:781–793.)
Research Sub Category
RNA Metabolism & Binding Proteins
Quality【质量】
Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected TNRC6B on 10 µg of HeLa cell lysate.
Physical form【外形】
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
Analysis Note【分析说明】
Control
HeLa cell lysate
Other Notes【其他说明】
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
产品性质
biological source【生物来源】
rabbit
Quality Level【质量水平】
100
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
purified by【纯化方式】
affinity chromatography
species reactivity
ox, human
species reactivity (predicted by homology)
mouse (based on 100% sequence homology), rat (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_001155973
UniProt accession no.【UniProt登记号】
Q9UPQ9
shipped in【运输】
wet ice
Gene Information
human ... TNRC6B(23112)
产品说明
Target description【目标描述】
~150/190 kDa observed. (Meister, G., et al. (2005). Current Biology. 15:2149–2155). An uncharacterized band at ~39 kDa may be observed in some lysates.
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
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