您的位置：首页 > 产品中心 > Anti-Vesicular GABA Transporter Antibody
Anti-Vesicular GABA Transporter Antibody
产品别名
Anti-Vesicular GABA Transporter Antibody
GABA and glycine transporter, Solute carrier family 32 member 1, Vesicular GABA transporter, solute carrier family 32 (GABA vesicular transporter), member 1, solute carrier family 32, member 1, vesicular inhibitory amino acid transporter
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
| General description【一般描述】 | Vesicular GABA transporter (VGAT), the first vesicular amino acid transporter to be molecularly identified, differs in structure from previously cloned vesicular neurotransmitter transporters and defines a novel gene family. VGAT is highly concentrated in the nerve endings of GABAergic neurons in the brain and spinal cord but also in glycinergic nerve endings. In contrast, hippocampal mossy fiber boutons, which are glutamatergic but known to contain GABA, lack VGAT immunoreactivity. Although the great majority of nerve terminals containing GABA or glycine are immunopositive for VGAT, subpopulations of nerve endings rich in GABA or glycine appear to lack the protein. Additional vesicular transporters or alternative modes of release may therefore contribute to the inhibitory neurotransmission mediated by these two amino acids. |
| Specificity【特异性】 | Cat. # AB2257 recognizes VGAT. |
| Immunogen【免疫原】 | Epitope: C-terminus KLH conjugated Vesicular GABA Transporter corresponding to the C-terminus. |
| Application【应用】 | Anti-Vesicular GABA Transporter Antibody is an antibody against Vesicular GABA Transporter for use in WB, IH. Research Category Neuroscience Research Sub Category Ion Channels & Transporters Immunohistochemistry Analysis: 1:50 - 1:500 dilution from a previous lot detected vesiluar GABA transporter using IHC-Select Detection with HRP-DAB. |
| Quality【质量】 | Routinely evaluated by Western Blot on rat brain lysates. Western Blot Analysis: 1:500 - 1:1,000 dilution of this lot detected vesicular GABA transporter on 10 µg of rat brain lysate. |
| Physical form【外形】 | Rabbit polyclonal serum in buffer containing 0.1M Tris-Glycine (pH7.4) 15mM NaCl with 0.05% NaN3. Antigen Affinity Purified |
| Analysis Note【分析说明】 | Control Rat brain lysate. |
| Other Notes【其他说明】 | Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration. |
产品性质
| biological source【生物来源】 | rabbit |
| Quality Level【质量水平】 | 100 |
| antibody form【抗体形式】 | serum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| species reactivity | rat |
| species reactivity (predicted by homology) | human, monkey |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| NCBI accession no.【NCBI登记号】 | NM_080552.2 |
| UniProt accession no.【UniProt登记号】 | Q9H598 |
| shipped in【运输】 | wet ice |
产品说明
| Target description【目标描述】 | Approx. 57 kDa |
| Storage and Stability【储存及稳定性】 | Stable for 1 year at 2-8ºC from date of receipt. |
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
