Daidzein-CAS 486-66-8-Calbiochem

C₁₅H₁₀O₄

254.24

MFCD00016954

Inactive analog of Genistein (Cat. No. 345834). Blocks the G₁ phase of the cell cycle in Swiss/3T3 cells by inhibiting casein kinase II activity. Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC₅₀= 45 µM and 75 µM, respectively).
Inactive analog of genistein (Cat. No. 345834). Blocks the G₁ phase of the cell cycle in Swiss 3T3 cells by inhibiting casein kinase II activity. Inhibits epidermal growth factor (EGF) receptor autophosphorylation (IC₅₀ >300 µM). Inhibits the growth of MiaPaC-2 and PANC-1 cells (IC₅₀= 45 µM and 75 µM, respectively).

Target IC₅₀: 45 µM, 75 µM for inhibiting the growth of MiaPaC-2 and PANC-1 cells, respectively
Primary Target
MiaPaC-2, PANC-1
Product does not compete with ATP.
Reversible: no
Cell permeable: no

Toxicity: Irritant (B)

Following reconstitution, aliquot and freeze (-20°C) under an inert gas. DMSO stock solutions are stable for up to 2 months at -20°C.

Guo, J-M., et al. 2004. World J. Gastroenterol.10, 860.
Higashi, K., and Ogawara, H. 1994. Biochim. Biophys. Acta 1221, 29.
Lavens, S.E., et al. 1992. Am. J. Respir. Cell Mol. Biol.7, 637.
Akiyama, T., et al. 1987. J. Biol. Chem.262, 5592.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥98% (TLC)

solid

Calbiochem^®

OK to freeze

off-white

DMSO: 200 mg/mL

ambient

−20℃

1S/C15H10O4/c16-10-3-1-9(2-4-10)13-8-19-14-7-11(17)5-6-12(14)15(13)18/h1-8,16-17H

ZQSIJRDFPHDXIC-UHFFFAOYSA-N

25 mg in Plastic ampoule
Packaged under inert gas

GHS07

Warning

H315 - H319

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

Eye Irrit. 2 - Skin Irrit. 2

11 - Combustible Solids

WGK 3