DL-α-Lipoic Acid, Dihydro--CAS 462-20-4-Calbiochem

C₈H₁₆O₂S₂

208.34

MFCD00166974

An effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α₁-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.
An effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α₁-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.

Product does not compete with ATP.
Reversible: no
Primary Target
Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals
Cell permeable: no

Toxicity: Irritant (B)

Packer, L., et al. 1997. Adv. Pharmacol. 38, 79.
Bustamante, J., et al. 1995. Free Radic. Biol. Med. 19, 339.
Scott, B.C., et al. 1994. Free Radic. Res. 20, 119.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥95% (TLC)

liquid

Calbiochem^®

OK to freeze
protect from light

light yellow

ethanol: 50 mg/mL

ambient

2-8℃

1S/C8H16O2S2/c9-8(10)4-2-1-3-7(12)5-6-11/h7,11-12H,1-6H2,(H,9,10)

IZFHEQBZOYJLPK-UHFFFAOYSA-N

50 mg in Plastic ampoule
Packaged under inert gas

GHS05,GHS07,GHS09

Danger

H302 - H315 - H317 - H318 - H411

P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

10 - Combustible liquids

WGK 2

348.1 °F - Cleveland open cup

175.6 ℃ - Cleveland open cup