您的位置：首页 > 产品中心 > 2353-33-5， InSolution 5-Aza-2'-Deoxycytidine-CAS 2353-33-5-Calbiochem
InSolution 5-Aza-2'-Deoxycytidine-CAS 2353-33-5-Calbiochem
| 产品编号： | 4157505 |
| 规格： | A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines. |
| CAS NO： | 2353-33-5 |
| 包装规格： | 10 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4157505 | 10 MG | 2300 |
产品别名
2353-33-5
InSolution 5-Aza-2'-Deoxycytidine-CAS 2353-33-5-Calbiochem
Decitabine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C8H12N4O4 |
| Molecular weight | 228.21 |
| MDL number | MFCD00043011 |
| General description【一般描述】 | A cytosine analog that acts as a DNA methyltransferase inhibitor. Restores caspase-8 and caspase-10 mRNA and protein expression as well as TRAIL (Tumor necrosis factor-Related Apoptosis Inducing Ligand) sensitivity in TRAIL-resistant cell lines. Also enhances apoptosis induced by HDAC (Histone Deacetylase) inhibitors. The solid form of this compound (Cat. No. 189825) is also available. |
| Warning【警告】 | Toxicity: Regulatory Review (Z) |
| Physical form【外形】 | A 100 mM (10 mg/438 µl) solution of 5-Aza-2ʹ-Deoxycytidine (Cat. No. 189825) in DMSO. |
| Other Notes【其他说明】 | Eggert, A., et al. 2001. Cancer Res.61, 1314. Takebayashi, S., et al. 2001. Biochem. Biophys. Res. Commun.288, 921. Zhu, W.G., et al. 2001. Cancer Res.61, 1327. Hopkins-Donaldson, S., et al. 2000. Cancer Res.60, 4315. Haaf, T. 1995. Pharmacol. Ther.65, 19. Jones, P.A., and Taylor, S.M. 1980. Cell20, 85. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated (hygroscopic) protect from light |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| InChI | 1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15) |
| InChI key | XAUDJQYHKZQPEU-UHFFFAOYSA-N |
| packaging【包装】 | 10 mg in Glass bottle Packaged under inert gas |
