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InSolution Tetrahydrouridine-CAS 18771-50-1-Calbiochem
| 产品编号： | 4157520 |
| 规格： | Tetrahydrouridine is a potent competitive inhibitor of cytidine deaminase. |
| CAS NO： | 18771-50-1 |
| 包装规格： | 25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 4157520 | 25 MG | 4130 |
产品别名
18771-50-1
InSolution Tetrahydrouridine-CAS 18771-50-1-Calbiochem
THU, H4U, 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-hydroxytetrahydropyrimidin-2(1H)-one, dihydrate
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C9H16N2O6 · 2H2O |
| Molecular weight | 284.26 |
| MDL number | MFCD00063468 |
| General description【一般描述】 | A potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies. The solid form of this compound (Cat. No. 584222) is also available. |
| Biochem/physiol Actions【生化/生理作用】 | Cell permeable: yes Reversible: yes Primary Target cytidine deaminase |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Physical form【外形】 | A 100 mM (25 mg/879 µL) solution of Tetrahydrouridine (Cat. No. 584222) in H₂O. |
| Reconstitution【重悬】 | Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C. |
| Other Notes【其他说明】 | Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun.206, 486. Bouffard, D.Y., et al. 1993. Biochem Pharmacol.45, 1857. Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol.30, 7. Riva, C., et al. 1992. Chemotherapy38, 358. Yusa, K., et al. 1992. J. Biol. Chem.267, 16848. Hanze, A.R. 1967. J. Am. Chem. Soc.89, 6720. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥90% (TLC) |
| form【形式】 | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze avoid repeated freeze/thaw cycles protect from light |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| SMILES string | OC1CCN([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C(N1)=O |
| InChI | 1S/C9H16N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4-8,12-15H,1-3H2,(H,10,16)/t4-,5?,6-,7-,8-/m1/s1 |
| InChI key | UCKYOOZPSJFJIZ-XVKVHKPRSA-N |
| packaging【包装】 | 25 mg in Glass bottle Packaged under inert gas |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
