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N-Methylated pomalidomide
产品别名
1352827-50-9
N-Methylated pomalidomide
Ligand for PROTAC research
E3 Ligase ligand methylated negative control
4-Amino-2-(1-methyl-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C14H13N3O4 |
| Molecular weight | 287.27 |
| NACRES | NA.22 |
| Application【应用】 | N-Methylated pomalidomide is a ligand used as a negative control for pomalidomide (P0018) in the recruitment of the Cereblon (CRBN) protein for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. |
| Other Notes【其他说明】 | Technology Spotlight: Degrader Building Blocks for Targeted Protein Degradation Portal: Building PROTAC® Degraders for Targeted Protein Degradation Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4 Targeted Protein Degradation by Small Molecules Small-Molecule PROTACS: New Approaches to Protein Degradation |
| Legal Information【法律信息】 | PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% |
| form【形式】 | powder or crystals |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O=C(C(CC1)N(C2=O)C(C3=C2C=CC=C3N)=O)N(C)C1=O |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
