PPARγ Antagonist III, G3335-CAS 36099-95-3-Calbiochem

C₁₆H₁₉N₃O₅

333.34

A cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist (K_D = ~ 8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC₅₀ = 31.9 µM) in transfected COS-7 cells.
A cell-permeable dipeptide that acts as a selective and reversible PPARγ antagonist (K_D ~8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC₅₀ = 31.9 µM) in transfected COS-7 cells.

Primary Target
PPARγ
Product does not compete with ATP.
Reversible: yes
Cell permeable: yes
kd = ~ 8 µM as PPARγ antagonist

Toxicity: Standard Handling (A)

Addition of a small amount of acid or base may be required for complete solubilization.

Following reconstitution aliquot freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.

Ye, F., et al. 2006. Chembiochem7, 74.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

100

≥97% (elemental analysis)

solid

Calbiochem^®

OK to freeze
protect from light

white

water: 30 mg/mL

ambient

2-8℃

50 mg in Plastic ampoule
Packaged under inert gas

11 - Combustible Solids

WGK 3