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Stearoyl-CoA Desaturase 1 Inhibitor, MF-438-Calbiochem
| 产品编号： | 4169394 |
| 规格： | Stearoyl-CoA Desaturase 1 Inhibitor, MF-438, CAS 921605-87-0, is a cell-permeable inhibitor of Stearoyl-CoA Desaturase 1 (SCD1; IC50 of 2.3 nM). |
| 包装规格： | 10 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Stearoyl-CoA Desaturase 1 Inhibitor, MF-438-Calbiochem
2-methyl-5-(6-(4-(2-(trifluoromethyl)phenoxy)piperidin-1-yl)pyridazin-3-yl)-1,3,4-thiadiazole
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H18F3N5OS |
| Molecular weight | 421.44 |
| General description【一般描述】 | A cell-permeable, thiadiazole-pyridazine compound that acts as an inhibitor of Stearoyl-CoA Desaturase 1 (SCD1) with an IC50 of 2.3 nM. In vivo, it exhibits an ED50 of 1-3 mg/kg, p.o., in mouse liver PD assays. |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Other Notes【其他说明】 | Leger, S., et al. 2010. Bioorg Med Chem Lett.2, 499. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥99% (HPLC) |
| form【形式】 | powder |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze |
| color【颜色】 | off-white |
| solubility【溶解性】 | DMSO: 10 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 10 mg in Glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 2 |
