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GW2974
| 产品编号： | 3094216 |
| 规格： | ≥98% (HPLC), solid |
| CAS NO： | 202272-68-2 |
| 包装规格： | 50 MG，250 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
202272-68-2
GW2974
N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethyl-pyrido-[3,4-d]-pyrimidine-4,6-diamine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C23H21N7 |
| Molecular weight | 395.46 |
| MDL number | MFCD04974495 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278451 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | Potent and selective dual inhibitor of EGFR (IC50 = 0.016 mM) and ErbB-2 receptor tyrosine kinase. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
| Legal Information【法律信息】 | Sold for research purposes under agreement from GlaxoSmithKline |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | yellow |
| solubility【溶解性】 | DMSO: ≥20 mg/mL |
| originator【创始人】 | GlaxoSmithKline |
| SMILES string | CN(C)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnc2cn1 |
| InChI | 1S/C23H21N7/c1-29(2)22-11-19-20(13-24-22)25-15-26-23(19)28-18-8-9-21-17(10-18)12-27-30(21)14-16-6-4-3-5-7-16/h3-13,15H,14H2,1-2H3,(H,25,26,28) |
| InChI key | DYYZXRCFCVDSKD-UHFFFAOYSA-N |
| Gene Information | human ... EGFR(1956), ERBB2(2064) |
| packaging【包装】 | 50, 250 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
