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Monoclonal Anti-Interleukin-18 Receptor antibody produced in mouse
| 产品编号： | 3147041 |
| 规格： | clone 70625.111, purified immunoglobulin, lyophilized powder |
| 包装规格： | 0.5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-Interleukin-18 Receptor antibody produced in mouse
Anti-IL-18 Receptor
基本信息
| MDL number | MFCD02096767 |
| NACRES | NA.41 |
| General description【一般描述】 | The antibody will neutralize the biological activity of recombinant human IL-18 receptor. |
| Immunogen【免疫原】 | recombinant human IL-18 receptor extracellular domain, expressed in NS0 cells. |
| Biochem/physiol Actions【生化/生理作用】 | IL-18 belongs to the IL-1 cytokine superfamily and is a regulator of innate and acquired immune responses. The immune responses of IL-18 are mediated by its interaction and subsequent signaling by IL-18 receptor complex. The IL-18R complex is made up of α chain that binds to extracellular IL-18 and a β chain that is involved in signal transduction. The IL-18/IL-18R signaling enhances T and NK cell maturation, cytotoxicity and secretion of cytokines. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose. |
| Preparation Note【制备说明】 | Purified using protein G. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 70625.111, monoclonal |
| form【形式】 | lyophilized powder |
| species reactivity | human |
| technique(s) | flow cytometry: suitable (2.5μg/SUP>106 cell) immunocytochemistry: 8-25 μg/mL immunohistochemistry: 8-25 μg/mL |
| isotype【同位素/亚型】 | IgG1 |
| UniProt accession no.【UniProt登记号】 | Q13478 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... IL18R1(8809) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
