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Monoclonal Anti-PLAGL1 antibody produced in mouse
产品别名
Monoclonal Anti-PLAGL1 antibody produced in mouse
Anti-ZAC
Anti-DKFZp781P1017
Anti-pleiomorphic adenoma gene-like 1
Anti-LOT1
Anti-ZAC1
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | 1E2, monoclonal |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgMκ |
| GenBank® accession no. | NM_002656 |
| UniProt accession no.【UniProt登记号】 | Q9UM63 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... PLAGL1(5325) |
基本信息
| General description【一般描述】 | This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activity. This gene has been shown to exhibit antiproliferative activities and is a tumor suppressor gene candidate. Many transcript variants encoding two different isoforms have been found for this gene. (provided by RefSeq) |
| Immunogen【免疫原】 | PLAGL1 (NP_002647.2, 221 a.a. ~ 320 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence QPMQPLPESLASLHPSVSPGSPPPPLPNHKYNTTSTSYSPLASLPLKADTKGFCNISLFEDLPLQEPQSPQKLNPGFDLAKGNAGKVNLPKELPADAVNL |
| Biochem/physiol Actions【生化/生理作用】 | The maternally-imprinted gene, PLAGL1 (pleiomorphic adenoma-like protein 1), functions as an oncogene as well as a tumor suppressor depending on the cell context. It has been found to exhibit anti-proliferative properties and regulate apoptosis and cell-cycle arrest via p53. |
| Physical form【外形】 | Solution |
| Legal Information【法律信息】 | GenBank is a registered trademark of United States Department of Health and Human Services |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
