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N6-Cyclopentyladenosine
产品别名
41552-82-3
N6-Cyclopentyladenosine
CPA
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C15H21N5O4 |
| Molecular weight | 335.36 |
| MDL number | MFCD00036845 |
| PubChem Substance ID【PubChem化学物质编号】 | 24277686 |
| NACRES | NA.77 |
| Application【应用】 | N6-Cyclopentyladenosine has been used to study its effect on the cavernosal smooth muscle cells from lean and db/db (obesity and type II diabetes caused by a leptin receptor mutation) mice. N6-Cyclopentyladenosine has also been used to study its effect on p53 and caspase 3, 8, and 9 expression and apoptosis rate in MCF-7 breast cancer cell line. |
| Biochem/physiol Actions【生化/生理作用】 | N6-Cyclopentyladenosine (CPA) is an adenosine derivative and a potent A1 adenosine receptor agonist. It acts as an anticonvulsant and might exhibit protective actions against aminophylline (AMPH)-induced seizures. N6-Cyclopentyladenosine also exhibits analgesic effect against acute, arthritis-induced and neuropathic pain. |
| Features and Benefits【特点和优势】 | This compound is featured on the Adenosine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
| Physical form【外形】 | hygroscopic solid |
产品性质
| Quality Level【质量水平】 | 200 |
| form【形式】 | solid |
| color【颜色】 | white to off-white |
| solubility【溶解性】 | H2O: 1.7 mg/mL 0.1 M HCl: 12 mg/mL DMSO: 23 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(NC4CCCC4)ncnc23 |
| InChI | 1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15-/m1/s1 |
| InChI key | SQMWSBKSHWARHU-SDBHATRESA-N |
| Gene Information | human ... ADORA1(134), ADORA2A(135), ADORA3(140) mouse ... Adora1(11539) rat ... Adora1(29290), Adora2a(25369), Adora3(25370) |
| packaging【包装】 | 25 mg in poly bottle 100 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
