您的位置：首页 > 产品中心 > 287204-45-9， PD-180970
PD-180970
产品别名
287204-45-9
PD-180970
PF-1515965
6-(2,6-Dichlorophenyl)-2-[(4-fluoro-3-methylphenyl)amino]-8-methyl-pyrido[2,3-d]pyrimidin-7(8H)-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H15Cl2FN4O |
| Molecular weight | 429.27 |
| MDL number | MFCD10565929 |
| PubChem Substance ID【PubChem化学物质编号】 | 329823727 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | PD-180970 is a potent inhibitor of the p210 Bcr-Abl tyrosine kinase. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
| Other Notes【其他说明】 | This compound was developed by Pfizer for Kinase Phosphatase Biology research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
| Legal Information【法律信息】 | Pfizer is a registered trademark of Pfizer, Inc. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| manufacturer/tradename | Pfizer® |
| color【颜色】 | yellow |
| solubility【溶解性】 | DMSO: >20 mg/mL |
| originator【创始人】 | Pfizer |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CN1C(=O)C(=Cc2cnc(Nc3ccc(F)c(C)c3)nc12)c4c(Cl)cccc4Cl |
| InChI | 1S/C21H15Cl2FN4O/c1-11-8-13(6-7-17(11)24)26-21-25-10-12-9-14(20(29)28(2)19(12)27-21)18-15(22)4-3-5-16(18)23/h3-10H,1-2H3,(H,25,26,27) |
| InChI key | SLCFEJAMCRLYRG-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 - H413 |
| Precautionary Statements | P273 - P301 + P310 + P330 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral - Aquatic Chronic 4 |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
