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RORγ 激活剂 1b
RORγ Activator 1b
产品别名
875286-88-7
RORγ 激活剂 1b
RORγ Activator 1b
N-(4,6-Dimethyl-2-benzothiazolyl)-3-methyl-2-thiophenecarboxamide
基本信息
| Empirical Formula【经验(实验)分子式】 | C15H14N2OS2 |
| Molecular weight | 302.41 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | RORγ Activator 1b binds to the retinoid-related orphan receptor RORγ and induces IL-17 reporter gene expression with an EC50 of 0.1 μM. The compound RORγ Activator 1b enhances differentiation of CD4+ T cells to IL-17-secreting cells with a maximum effect of 220 percent of control at 3 μM. |
产品性质
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 20 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
