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THPN
产品别名
100079-26-3
THPN
1-(2,4,6-Trihydroxyphenyl)-1-nonanone
CID 3063200
1-(3,4,5-Trihydroxyphenyl)nonan-1-one
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C15H22O4 |
| Molecular weight | 266.33 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825957 |
| NACRES | NA.77 |
| General description【一般描述】 | THPN or 1-(3,4,5-Trihydroxyphenyl)nonan-1-one, is a derivative of cytosporone B. |
| Biochem/physiol Actions【生化/生理作用】 | THPN is potent nuclear receptor TR3 (Nur77) antagonist that induces autophagic cell death in melanoma. Co-application of THPN with Akt2 inhibitors significantly represses tumor growth in xenograft mouse model. |
| Other Notes【其他说明】 | air sensitive |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: 25 mg/mL, clear |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | OC1=C(O)C(O)=CC(C(CCCCCCCC)=O)=C1 |
| InChI | 1S/C15H22O4/c1-2-3-4-5-6-7-8-12(16)11-9-13(17)15(19)14(18)10-11/h9-10,17-19H,2-8H2,1H3 |
| InChI key | NVFRHTFJDGAFQS-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Precautionary Statements | P301 + P312 + P330 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
