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Tofisopam
| 产品编号： | 3253442 |
| 规格： | ≥98% (HPLC), solid |
| CAS NO： | 22345-47-7 |
| 包装规格： | 10 MG，50 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3253442 | 10 MG | 1810 | 2-5天 | 4-6周 | |
| 3253442 | 50 MG | 6560 | 2-5天 | 4-6周 |
产品别名
22345-47-7
Tofisopam
7,8-Dimethoxy-1-(3,4-dimethoxyphenyl)-5-ethyl-4-methyl-5H-2,3-benzodiazepine
EGYT 341
Seriel
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C22H26N2O4 |
| Molecular weight | 382.45 |
| EC number【EC 号】 | 244-922-3 |
| MDL number | MFCD00823171 |
| PubChem Substance ID【PubChem化学物质编号】 | 24724636 |
| NACRES | NA.77 |
| Application【应用】 | Tofisopam has been used for studying its biochemical mechanisms of actions using drug repositioning strategies. |
| Biochem/physiol Actions【生化/生理作用】 | Studies have reported that tofisopam functions by blocking PDE4 (phosphodiesterase 4). Furthermore, the S-enantiomer of tofisopam is considered ten times more active than R-enantiomer. Ligand for the GABAA receptor benzodiazepine modulatory site. |
| Preparation Note【制备说明】 | Tofisopam is soluble in DMSO at approximately 14 mg/ml. However, it is insoluble in water. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| drug control | regulated under CDSA - not available from sigma-aldrich Canada |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: ~14 mg/mL H2O: insoluble |
| SMILES string | CCC1C(C)=NN=C(c2ccc(OC)c(OC)c2)c3cc(OC)c(OC)cc13 |
| InChI | 1S/C22H26N2O4/c1-7-15-13(2)23-24-22(14-8-9-18(25-3)19(10-14)26-4)17-12-21(28-6)20(27-5)11-16(15)17/h8-12,15H,7H2,1-6H3 |
| InChI key | RUJBDQSFYCKFAA-UHFFFAOYSA-N |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07,GHS09 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 - H400 |
| Precautionary Statements | P273 - P301 + P312 + P330 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Aquatic Acute 1 |
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 2 |
| Personal Protective Equipment【个人防护装备】 | dust mask type N95 (US), Eyeshields, Gloves |
