Valnoctamide

C₈H₁₇NO

143.23

MFCD00868184

329829054

NA.77

Valnoctamide has been used:

• as a mood stabilizer to study its anti-cytomegalovirus (anti-CMV) effects in newborn mice brain
• as a hypnotic sedative to study its cytotoxic effects on oligodendrocyte precursor cells (OPCs) and human oligodendroglioma cell line (HOG)
• as a mood stabilizer to study its effects on inhibition of human cytomegalovirus

Valproic acid (VPA) and derivatives such as valpromide and valnoctamide are anti-convulsant, mood stabilizing drugs, believed to function as indirect GABA agonists by inhibiting the transamination of GABA.
Valnoctamide exhibits anti-cytomegalovirus (anti-CMV) properties. It has therapeutic effects against status epilepticus (SE) and neuropathic pain. Valnoctamide also shows therapeutic effects against bipolar disorders.

This compound is featured on the Glutamate/GABA Synthesis and Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

100

≥98% (NMR)

powder

desiccated

white to off-white

DMSO: 20 mg/mL, clear

room temp

CCC(C)C(CC)C(N)=O

1S/C8H17NO/c1-4-6(3)7(5-2)8(9)10/h6-7H,4-5H2,1-3H3,(H2,9,10)

QRCJOCOSPZMDJY-UHFFFAOYSA-N

5, 25 mg in glass bottle

GHS07

Warning

H302

Acute Tox. 4 Oral

11 - Combustible Solids

WGK 3