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(R)-3-氨基-1-叔丁氧羰基哌啶
(R)-(-)-3-Amino-1-Boc-piperidine
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3323810 | 1G-F | 1900 | 2-5天 | 4-6周 |
产品别名
188111-79-7
(R)-3-氨基-1-叔丁氧羰基哌啶
(R)-(-)-3-Amino-1-Boc-piperidine
(R)-1-Boc-3-piperidinamine
tert-Butyl (R)-3-amino-1-piperidinecarboxylate
(R)-1-Boc-3-氨基哌啶
(R)-1-叔丁氧羰基-3-氨基哌啶
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C10H20N2O2 |
| Molecular weight | 200.28 |
| MDL number | MFCD03094717 |
| PubChem Substance ID【PubChem化学物质编号】 | 329748523 |
| NACRES | NA.22 |
| General description【一般描述】 | (R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents. |
| Application【应用】 | (R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98.0% (TLC) |
| optical activity【旋光性】 | [α]/D -28.5±2°, c = 1 in DMF |
| SMILES string | CC(C)(C)OC(=O)N1CCC[C@@H](N)C1 |
| InChI | 1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1 |
| InChI key | AKQXKEBCONUWCL-MRVPVSSYSA-N |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语:】 | Warning |
| Hazard Statements | H302 - H315 - H319 - H335 |
| Precautionary Statements | P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3 |
| Target Organs【靶器官】 | Respiratory system |
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter |




