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AC-265347
产品别名
AC-265347
1-(1,3-benzothiazol-2-yl)-1-(2,4-dimethylphenyl)ethanol, a-(2,4-Dimethylphenyl)-a-methyl-2-benzothiazolemethanol.
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H17NOS |
| Molecular weight | 283.39 |
| MDL number | MFCD20527324 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825179 |
| NACRES | NA.77 |
| Application【应用】 | AC-265347 may be used in calcium-sensing receptor-mediated signaling. |
| Biochem/physiol Actions【生化/生理作用】 | AC-265347 is a calcimimetic that acts as agonist to calcium-sensing receptor. It reduces serum parathyroid hormone and plasma ionizable calcium. AC-265347 is a human calcium-sensing receptor (CaSR) allosteric agonist. AC-265347 activates CaSR signaling in cellular proliferation and phosphatidyl inositol (PI) hydrolysis assays. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to tan |
| solubility【溶解性】 | DMSO: ≥19 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | Cc1ccc(c(C)c1)C(C)(O)c2nc3ccccc3s2 |
| InChI | 1S/C17H17NOS/c1-11-8-9-13(12(2)10-11)17(3,19)16-18-14-6-4-5-7-15(14)20-16/h4-10,19H,1-3H3 |
| InChI key | IGSZVEPQZANNAB-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
