(Tributylphosphoranylidene)acetonitrile

C₁₄H₂₈NP

241.35

NA.22

(Tributylphosphoranylidene)acetonitrile or cyanomethylenetrimethylphosphorane (Bu₃P=CHCN) is a Wittig reagent employed in the transformation of the carbonyl compounds, including aldehydes, esters, and lactones into the corresponding unsaturated nitriles.

(Tributylphosphoranylidene)acetonitrile can be utilized as a reagent in the:

• Stereoselective synthesis of skytanthine and other O- and N-containing heterocycles by Mitsunobu intramolecular cycloalkylation.
• Wittig olefination of esters, lactones, N-Boc lactam, and cyclic imide to corresponding Wittig products.

100

97%

liquid

n20/D 1.500 (lit.)

0.921 g/mL at 25 ℃

2-8℃

1 g in glass bottle
500 mg in glass bottle

12 - Non Combustible Liquids

WGK 3