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Anti-ADFP antibody produced in mouse
| 产品编号： | 3343517 |
| 规格： | purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 50 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-ADFP antibody produced in mouse
ADRP
MGC10598
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | Adipocyte differentiation-related protein is associated with the globule surface membrane material. This protein is a major constituent of the globule surface. Increase in mRNA levels is one of the earliest indications of adipocyte differentiation (provided by RefSeq) Adipose differentiation-related protein (ADRP), also known as adipose differentiation-related protein (ADFP), is the major lipid droplet protein. It is encoded by the gene mapped to human chromosome 9p22.1–p21.3. ADFP is ubiquitously expressed and is a member of PAT (perilipin/APRP/TIP47) family. |
| Immunogen【免疫原】 | ADFP (NP_001113.2, 1 a.a. ~ 437 a.a) full-length human protein. Sequence MASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVAMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTESQNAQDQGAEMDKSSQETQRSEHKTH |
| Biochem/physiol Actions【生化/生理作用】 | Adipose differentiation-related protein (ADFP) plays a vital role in lipid droplet (LD) formation and/or maturation. Increased expression of this protein in tamm-horsfall protein 1 (THP-1) macrophages increases lipid accumulation and stops lipid efflux. In addition, ADFP is slightly involved in maintenance of adipose tissue homeostasis. It acts as a potential marker for intracellular LD in tissues. |
| Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
产品性质
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | buffered aqueous solution |
| mol wt【分子量】 | antigen ~48.1 kDa |
| species reactivity | human |
| technique(s) | western blot: 1 μg/mL |
| NCBI accession no.【NCBI登记号】 | NM_001122.2 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... ADFP(123) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
