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Anti-Interleukin-5 antibody produced in goat
| 产品编号： | 3370120 |
| 规格： | IgG fraction of antiserum, lyophilized powder |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Anti-Interleukin-5 antibody produced in goat
Anti-IL-5
基本信息
| MDL number | MFCD00212216 |
| NACRES | NA.41 |
| General description【一般描述】 | The antibody neutralizes the biological activity of recombinant human IL-5. |
| Immunogen【免疫原】 | recombinant human IL expressed in Sf 21 insect cell line. |
| Biochem/physiol Actions【生化/生理作用】 | Interleukin-5 is a T-cell derived cytokine that induces the differentiation of B cells into antibody producing plasma cells. It is a critical differentiation factor for eosinophils and regulates the expression of genes required for cell proliferation, survival and maturation. The cellular functions of IL-5 are mediated by JAK-STAT, Btk and Ras/Raf-ERK signaling pathways. IL-5 is a good molecular target for the treatment of eosinophilic diseases. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline. |
| Preparation Note【制备说明】 | Purified using protein G. |
产品性质
| Quality Level【质量水平】 | 200 |
| biological source【生物来源】 | goat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone【克隆】 | polyclonal |
| form【形式】 | lyophilized powder |
| species reactivity | human |
| technique(s) | indirect ELISA: 0.5-1.0 μg/test neutralization: suitable western blot: 1-2 μg/mL |
| UniProt accession no.【UniProt登记号】 | P05113 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... IL5(3567) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 2 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
