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产品别名
104615-18-1
CGS-15943
9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C13H8ClN5O |
| Molecular weight | 285.69 |
| MDL number | MFCD01529897 |
| PubChem Substance ID【PubChem化学物质编号】 | 24277704 |
| NACRES | NA.77 |
| Application【应用】 | CGS-15943 has been used as a non-selective adenosine receptor antagonist to study its effects on the proliferation of pancreatic ductal adenocarcinoma (PDAC) cells and hepatocellular carcinoma (HCC). It has also been used as a non-selective adenosine receptor antagonist to investigate the mechanism underlying adenosine inhibition on cholangiocarcinoma (CCA) cells. |
| Biochem/physiol Actions【生化/生理作用】 | CGS-15943 is a potent and non-selective adenosine receptor antagonist. It exhibits anti-carcinogenic and anti-apoptotic activity. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| color【颜色】 | white |
| solubility【溶解性】 | DMSO: >10 mg/mL H2O: insoluble |
| storage temp.【储存温度】 | room temp |
| SMILES string | Nc1nc2ccc(Cl)cc2c3nc(nn13)-c4ccco4 |
| InChI | 1S/C13H8ClN5O/c14-7-3-4-9-8(6-7)12-17-11(10-2-1-5-20-10)18-19(12)13(15)16-9/h1-6H,(H2,15,16) |
| InChI key | MSJODEOZODDVGW-UHFFFAOYSA-N |
| Gene Information | human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140) rat ... Adora1(29290), Adora2a(25369), Adora2b(29316) |
| packaging【包装】 | 25 mg in poly bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
