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磷酸化EGFR(pTyr1068) 和pan-EGFR ELISA试剂盒
Phospho-EGFR (pTyr1068) and pan-EGFR ELISA Kit
| 产品编号： | 4068328 |
| 规格： | for detection of human phospho-egfr (pTyr1068) and pan-egfr in cell and tissue lysates |
| 包装规格： | 1 KIT |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
磷酸化EGFR(pTyr1068) 和pan-EGFR ELISA试剂盒
Phospho-EGFR (pTyr1068) and pan-EGFR ELISA Kit
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | The Phospho-EGFR (pTyr1068) ELISA (Enzyme-Linked Immunosorbent Assay) kit is a very rapid, convenient and sensitive assay kit that can monitor the activation or function of important biological pathways in cell lysates. |
| Immunogen【免疫原】 | EGFR (pTyr1068) synthetic phosphopeptide, Recombinant Human EGFR |
| Application【应用】 | 请参考Protocol了解详情。 |
| Biochem/physiol Actions【生化/生理作用】 | EGFR (epidermal growth factor receptor) functions as a receptor for EGF-family of proteins, which are peptide growth factors. This receptor-ligand system is also involved in the pathogenesis and progression of various types of carcinomas. In cancer, EGFR pathways promotes cellular proliferation, angiogenesis, metastasis and apoptosis. The microRNA miR-218-5p interacts with and controls EGFR, and in non-small cell lung cancer (NSCLC), the levels of EGFR are inversely related to miR-218-5p. miR-218-5p inhibits proliferation and migration of lung cancer cells by binding with EGFR, and thus, has potential in future NSCLC therapies. Phospho-EGFR activates phospho-Akt pathway in invasive bladder cancer (BC) and it can be considered as a promising therapeutic target for cancer. |
| Other Notes【其他说明】 | Phosphorylated and pan protien can both be measured , in one experimnet. |
产品性质
| species reactivity | human |
| packaging【包装】 | kit of 96 wells (12 strips x 8 wells) |
| technique(s) | ELISA: suitable capture ELISA: suitable |
| input | sample type: human cell lysate sample type: human tissue lysate |
| Detection Method | colorimetric |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... EGFR(1965) |
安全信息
| Pictograms【象形图】 | GHS05 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H290 |
| Hazard Classifications【危险分类】 | Met. Corr. 1 |
| Storage Class Code【储存分类代码】 | 8B - Non-combustible, corrosive hazardous materials |
