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1-desoxymethylsphingosine
| 产品编号： | 4069553 |
| 规格： | 1-desoxymethylsphingosine (m17:1), powder |
| CAS NO： | 1246303-16-1 |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品别名
1246303-16-1
1-desoxymethylsphingosine
1-Deoxymethylsphingosine
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C17H35NO |
| Molecular weight | 269.47 |
| NACRES | NA.25 |
| General description【一般描述】 | 1-desoxymethylsphingosine is synthesized from glycine in the presence of the enzyme serine palmitoyltransferase (SPT). |
| Application【应用】 | 1-desoxymethylsphingosine may be used for the complex preparation with bovine serum albumin for cytotoxicity testing in MN9D dopaminergic neuroblastoma cell line. |
| Biochem/physiol Actions【生化/生理作用】 | 1-desoxymethylsphingosine is less neurotoxic compared to 1-desoxysphingosine in dorsal root ganglion neuronscultures Mutations in the palmitoyltransferase (SPT) in hereditary sensory neuropathy type 1 (HSAN-1), due to altered substrate specificity 1-desoxymethylsphinganine and 1-deoxy-sphinganine which are further converted to -deoxy(methyl)-ceramide and 1-deoxy(methyl)-sphingosine (1-deoxy(methyl)-SO). However, they lack the hydroxyl group essential for glycosphingolipid generation, resulting in accumulation of intermediate products. |
产品性质
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 860477P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | CCCCCCCCCCCCC/C=C/[C@](O)([H])CN |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (860477P-1mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
