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Ligstroside
| 产品编号： | 4073852 |
| 规格： | Nitric oxide inhibitor, ≥95% |
| CAS NO： | 35897-92-8 |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
35897-92-8
Ligstroside
Ligustroside
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C25H32O12 |
| Molecular weight | 524.51 |
| Biochem/physiol Actions【生化/生理作用】 | Ligstroside is a natural product derived from leaves of Olea europaea. Ligstroside displays several potentially beneficial anti-inflammatory properties by exhibiting selective inhibition effect on COX-1 enzyme of arachidonate cascade metabolism. Ligstroside generates a reduction of the PGE2 (prostaglandin E2) levels in activated mouse macrophage (IC50 = 48.53 μM) and also reduction of the TXB2 (thromboxane B2) levels in human platelets (IC50 = 122.63 μM). Moreover, Ligstroside exhibits inhibition activity of NO production in LPS-activated RAW264.7 macrophages (17.8% at 30 μM and 40.7% at 100 μM) without any cytotoxic effect in these cells., Additionally, Ligstroside exhibits in vitro antiviral activity against parainfluenza type 3 virus (IC50 = 15.6 μM). |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥95% |
| form【形式】 | lyophilized powder |
| solubility【溶解性】 | DMSO: ≥10 mg/mL (19 mM) methanol: ≥10 mg/mL |
| storage temp.【储存温度】 | −20℃ |
产品说明
| Storage and Stability【储存及稳定性】 | Hygroscopic; store in dry place with desiccant |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
