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Caspase-3 Inhibitor III-CAS 285570-60-7-Calbiochem
| 产品编号： | 4073883 |
| 规格： | The Caspase-3 Inhibitor III, also referenced under CAS 285570-60-7, controls the biological activity of Caspase-3. This small molecule/inhibitor is primarily used for Cancer applications. |
| CAS NO： | 285570-60-7 |
| 包装规格： | 1 MG，5 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
285570-60-7
Caspase-3 Inhibitor III-CAS 285570-60-7-Calbiochem
Ac-DEVD-CMK
基本信息
| Empirical Formula【经验(实验)分子式】 | C21H31ClN4O11 |
| Molecular weight | 550.94 |
| General description【一般描述】 | A potent cell-permeable and irreversible inhibitor of caspase-3, a member of the ICE-CED-3 family of cysteine proteases. A potent, cell-permeable, and irreversible inhibitor of caspase-3 as well as caspase-6, caspase-7, caspase-8, and caspase-10. |
| Biochem/physiol Actions【生化/生理作用】 | Cell permeable: yes Product does not compete with ATP. Reversible: no Primary Target caspase-3, caspase-6, caspase-7, caspase-8, caspase-10 |
| Warning【警告】 | Toxicity: Standard Handling (A) |
| Sequence【序列】 | Ac-Asp-Glu-Val-Asp-CMK |
| Reconstitution【重悬】 | Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C. |
| Other Notes【其他说明】 | Mocanu, M.M., et al. 2000. Br. J. Pharmacol.130, 197 Schrantz, N., et al. 1999. Cell Death Differ. 6, 445. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. |
| Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | lyophilized solid powder |
| manufacturer/tradename | Calbiochem® |
| storage condition【储存条件】 | OK to freeze desiccated |
| color【颜色】 | white to off-white |
| solubility【溶解性】 | 20% acetonitrile: 1 mg/mL |
| shipped in【运输】 | ambient |
| storage temp.【储存温度】 | −20℃ |
| packaging【包装】 | 1, 5 mg in Plastic ampoule |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 1 |
