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[Gly22]-Amyloid β 1-40 Arctic human
基本信息
| Empirical Formula【经验(实验)分子式】 | C191H291N53O56S1 |
| Molecular weight | 4257.74 |
| Amino Acid Sequence | Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gly-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val |
| General description【一般描述】 | β-Amyloid peptides are the major constituents of senile plaques and neurofibrillary tangles that occur in the hippocampus, neocortex, and amygdala of patients with Alzheimer′s disease. Aβ (1-40) whether soluble or insoluble differentiates AD vs high pathology controls. The Arctic mutation E22G causes early onset of Alzheimer′s compared to wild type and promotes protofibril formation and neurotoxicity. |
产品性质
| Assay【测定】 | ≥95% (HPLC) |
| form【形式】 | lyophilized |
| composition【组成】 | Peptide Content, ≥75% |
| storage condition【储存条件】 | protect from light |
| UniProt accession no.【UniProt登记号】 | P05067 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... APP(351) |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
