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CIRBP/冷诱导 RNA 结合蛋白 人
CIRBP/Cold-inducible RNA-binding protein human
| 产品编号： | 4077522 |
| 规格： | recombinant, expressed in E. coli, ≥90% (SDS-PAGE) |
| 包装规格： | 20 μG，100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
CIRBP/冷诱导 RNA 结合蛋白 人
CIRBP/Cold-inducible RNA-binding protein human
A18HNRNP
CIRP
基本信息
| NACRES | NA.32 |
| General description【一般描述】 | CIRBP, also known as cold-inducible RNA-binding protein, plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. CIRBP responds to a wide array of cellular stresses, including short wavelength ultraviolet light (UVC), at the transcriptional and post-translational level. It acts as a translational activator. CIRBP can bind the 3′untranslated region of specific transcripts to stabilize them and facilitate their transport to ribosomes for translation. CIRBP affects NF-κB signaling as opposed to IL1B mRNA stability directly. |
| Physical form【外形】 | Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 0.25 M Imidazole, 20% glycerol. |
| Reconstitution【重悬】 | Detailed reconstitution instructions are sent along with the product |
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in E. coli |
| Assay【测定】 | ≥90% (SDS-PAGE) |
| form【形式】 | lyophilized |
| mol wt【分子量】 | 20.5 kDa |
| packaging【包装】 | pkg of 1 mg pkg of 20 μg |
| impurities【杂质】 | ≤1 EU/μg endotoxin (LAL test) |
| UniProt accession no.【UniProt登记号】 | Q14011 |
| shipped in【运输】 | wet ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... CIRBP(1153) |
安全信息
| Pictograms【象形图】 | GHS07,GHS08 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H315 - H319 - H360D |
| Precautionary Statements | P201 - P280 - P305 + P351 + P338 - P308 + P313 - P337 + P313 |
| Hazard Classifications【危险分类】 | Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 |
| Storage Class Code【储存分类代码】 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
