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STAT2 human
| 产品编号： | 4084955 |
| 规格： | recombinant, expressed in insect cells, ≥80% (SDS-PAGE) |
| 包装规格： | 5 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
STAT2 human
MGC59816
ISGF-3
STAT113
p113
产品性质
| biological source【生物来源】 | human |
| recombinant【重组】 | expressed in insect cells |
| Assay【测定】 | ≥80% (SDS-PAGE) |
| form【形式】 | frozen liquid |
| mol wt【分子量】 | ~101 kDa |
| packaging【包装】 | pkg of 5 μg |
| storage condition【储存条件】 | avoid repeated freeze/thaw cycles |
| concentration【浓度】 | 800 μg/mL |
| color【颜色】 | clear colorless |
| NCBI accession no.【NCBI登记号】 | NM_005419 |
| UniProt accession no.【UniProt登记号】 | P52630 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −70℃ |
| Gene Information | human ... STAT2(6773) |
基本信息
| Biochem/physiol Actions【生化/生理作用】 | The signal transducer and activator of transcription (STAT) proteins play a crucial role in the regulation of gene expression by mediating transcriptional responses to many cytokines and growth factors. The antiviral responses of IFN-α/β rely on the transcriptional activities of STAT1 and STAT2 proteins. The chromatin immunoprecipitation and DNA microarray analysis (Chip-chip) demonstrated that STAT2 (and STAT1) bound to chromosome 22 after IFN stimulation. STAT2 activity can be regulated by tyrosine phosphorylation that is catalyzed by a receptor associated JAK kinase. |
| Physical form【外形】 | Clear and colorless frozen liquid solution |
| Preparation Note【制备说明】 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice. |
安全信息
| Storage Class Code【储存分类代码】 | 10 - Combustible liquids |
| WGK | WGK 1 |
