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VPC 12249 (S)
| 产品编号： | 4095784 |
| 规格： | (S)-phosphoric acid mono-[3-(4-benzyloxy-phenyl)-2-octadec-9-enoylamino-propyl] ester (ammonium salt), powder |
| CAS NO： | 799268-73-8 |
| 包装规格： | 1 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Avanti |
| 优惠价： | 立即咨询 |
产品别名
799268-73-8
VPC 12249 (S)
[(2S)-2-[[(Z)-octadec-9-enoyl]amino]-3-(4-phenylmethoxyphenyl)propyl] hydrogen phosphate
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C34H55N2O6P |
| Molecular weight | 618.78 |
| NACRES | NA.25 |
| General description【一般描述】 | VPC 12249 is an N-acyl (oleoyl) serine phosphate-based compound. |
| Application【应用】 | VPC 12249 has been used as lysophosphatidic acid (LPA)1/3 receptor antagonist in various experimental studies. |
| Biochem/physiol Actions【生化/生理作用】 | Lysophosphatidic acids (LPAs) are bioactive lipid mediators. It interacts with at least six specific LPA receptors (LPA1-6) to mediate extracellular signaling pathway. LPA and its receptors (LPA1-3) are implicated in the pathogenesis of radiation pneumonitis (RP). VPC 12249 (S) inhibits the binding ofLPA to LPA1 and LPA3 receptor. |
产品性质
| Assay【测定】 | >99% (TLC) |
| form【形式】 | powder |
| manufacturer/tradename | Avanti Polar Lipids 857341P |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| SMILES string | O=C(CCCCCCC/C=C\CCCCCCCC)N[C@H](COP(O)([O-])=O)CC1=CC=C(OCC2=CC=CC=C2)C=C1.[NH4+] |
| packaging【包装】 | 5 mL Amber Glass Screw Cap Vial (857341P-1mg) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
