产品编号：4083569

包装规格：5 MG

产品编号：4083567

纯度规格：A cell-permeable compound that prevents various bacterial toxins from exerting their cytotoxic activity by blocking endosomal trafficking/maturation into acidified late endosomes.

包装规格：25 MG

产品编号：4083565

纯度规格：A fast acting, reversible, and selective activator of Kir6.2/SUR1 channels (EC₅₀ = 7 μM).

包装规格：10 MG

产品编号：4083563

纯度规格：A cell-permeable, direct, non-covalent inhibitor of Keap1-Nrf2 protein-protein interaction (Kd = 1 μM) that causes the dissociation of Nrf2 from keap1 in the cytosol.

包装规格：10 MG

产品编号：4083562

包装规格：10 MG

产品编号：4083561

包装规格：5 MG

产品编号：4083560

纯度规格：A cell-permeable, superior inhibitor of Jumonji C domain histone lysine demethylase. About 30 fold more potent than IOX1 (EC₅₀ = 3.8 μM for KDM4A in HeLa cells vs. 100 μM for IOX1).

包装规格：10 MG

产品编号：4083558

纯度规格：A cell permeable analog of curcumin that acts as a specific inhibitor of JAK2 (~ 5 μM) and blocks STAT3 phosphorylation in MDA-MB-231 and PANC-1 cancer cells.

包装规格：25 MG

产品编号：4083557

纯度规格：The cell-permeable, selective inhibitor of eIF2α/eIF2S1 Ser51 phosphorylation-initiated UPR response (~25 to 200 nM) upon ER stress induction.

包装规格：10 MG

产品编号：4083556

纯度规格：InSolution^TM Y-27632, Sterile-Filtered, Cell Culture-Tested, CAS 146986-50-7, is a 10 mM sterile-filtered solution of Y-27632 in H₂O. Acts as an inhibitor of Rho kinases (Ki = 140 nM for p160ROCK).

包装规格：2 MG

产品编号：4083555

纯度规格：A 25 mM (2 mg/221 μL) sterile-filtered solution of TLR4 Inhibitor, TAK-242 in DMSO.

包装规格：2 MG

产品编号：4083553

纯度规格：A 25 mM (10 mg/650 μl) sterile-filtered solution of SRT1720, HCl in DMSO.

包装规格：10 MG

产品编号：4083552

纯度规格：A 25 μM (10 mg/583 μL) sterile-filtered solution of Pepstatin A, Synthetic in DMSO.

包装规格：10 MG

产品编号：4083551

包装规格：500 μG

产品编号：4083550

包装规格：5 MG

产品编号：4083549

纯度规格：A 25 mM (1 mg/98 μL) sterile-filtered solution of Histone Methyltransferase EZH2 Inhibitor, DZNep in H₂O.

包装规格：1 MG

产品编号：4083547

纯度规格：A 50 mM (2 mg/106.23 μL) sterile-filtered solution of APT1 Inhibitor, palmostatin B in DMSO.

包装规格：2 MG

产品编号：4083546

纯度规格：A 30 mM (1 mg/98 μL) sterile-filtered solution of Aphidicolin in DMSO.

包装规格：1 MG

产品编号：4083545

纯度规格：A cell-permeable, selective inhibitor of E3 ligase complex SCFβTrCP1-mediated ubiquitination of phosphorylated IκBα (IC₅₀ = 5.2 μM).

包装规格：10 MG

产品编号：4083542

纯度规格：A cell-permeable inhibitor of isocitrate dehydrogenase 2 R140Q mutant-containing dimers. Has minimal effect on wild type dimer-catalyzed alpha-KG production.

包装规格：10 MG

产品编号：4083539

纯度规格：A cell-permeable 6-amino-purine based compound that selectively binds to HSP90a (EC₅₀ = 5.4 μM) and inhibits its activity cancer cells.

包装规格：5 MG

产品编号：4083534

纯度规格：A cell-permeable, highly potent, and selective agonist of free fatty acid receptor 1 (FFA1; GPR40; EC₅₀ = 20 nM in FFA1-transfected HEK-293 cells).

包装规格：10 MG

产品编号：4083533

包装规格：10 MG

产品编号：4083532

包装规格：10 MG

产品编号：4083527

包装规格：10 MG

产品编号：4083525

纯度规格：A helical 27-mer peptide with E54Q modification that directly binds to EDD (Kd = 320 nM) and disrupts protein-protein interaction of EED with EZH2 and EZH1.

包装规格：2 MG

产品编号：4083524

纯度规格：A cell-permeable inhibitor of Eya2 ED tyrosine phosphatase (IC₅₀ = 4.1 μM; KD = 2.0 μM for hEya2, catalytic domain)

包装规格：25 MG

产品编号：4083523

纯度规格：A cell-permeable compound that reversibly blocks cellular glycosylation and surface expression of Notch, APP, Klotho by blocking events prior to cargo assembly at the ER exit sites.

包装规格：10 MG

产品编号：4083522

纯度规格：A cell-permeable antagonist of Eph receptors that competitively disrupts Eph2A-ephrin-A1 binding (IC₅₀ = 945 nM; K_i = 345 nM).

包装规格：10 MG

产品编号：4083521

纯度规格：A nitro-benzoxadiazole compound that directly binds to the dimerization domain of sEGF receptor to generate stable dimers and allosterically activate the receptor.

包装规格：25 MG

产品编号：4083516

包装规格：50 MG

产品编号：4083515

纯度规格：An immunosuppressive and anti-neoplastic agent that inhibits pyrimidine synthesis by blocking the activity of mammalian mitochondrial dihydroorotate dehydrogenase (DHODH; IC₅₀ = 12 nM).

包装规格：10 MG

产品编号：4083514

纯度规格：An agonist of mammalian Diaphanous (mDia)-related formins that disrupts diaphanous inhibitory domain (DID) and diaphanous autoregulatory domain (DAD) interaction (IC₅₀ = 140 nM).

包装规格：10 MG

产品编号：4083508

纯度规格：A cell-permeable, selective allosteric inhibitor of E2 ubiquitin-conjugating enzyme Cdc34 (IC₅₀ = 2.5 μM in a Sic1-SCFCdc4 assay).

包装规格：10 MG

产品编号：4083507

纯度规格：A cell-permeable compound that specifically targets TRAF6 (Kd = 97 μM for TRAF6 C-domain) and disrupts its functional coupling with CD40.

包装规格：25 MG

产品编号：4083506

包装规格：10 MG

产品编号：4083505

纯度规格：A set of PYR6, a CRAC Channel Inhibitor III; and PYR10, a TPRC3 Channel Inhibitor III.

包装规格：1 SET

产品编号：4083504

纯度规格：A cell-permeable, orally available, non-competitive antagonist of C5a receptor (CD88; IC₅₀ = 240 nM) and as a low-affinity agonist for MrgX2.

包装规格：10 MG

产品编号：4083503

包装规格：10 MG

产品编号：4083502

纯度规格：A cell-permeable compound that directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding and transcriptional activity (IC₅₀ = 3 μM).

包装规格：10 MG

产品编号：4083501

纯度规格：KJ-Pyr-9, C-Myci

包装规格：10 MG

产品编号：4083499

纯度规格：An antagonist of muscarinic M1 and M3 receptors that induces robust differentiation of oligodendrocytes precursor cell differentiation (EC₅₀ = 500 nM) and promotes myelination.

包装规格：50 MG

产品编号：4083498

纯度规格：Beclin-1 Activator I, TAT-Beclin-1, is a cell-permeable Atg6/Beclin1-derived autophagy-inducing peptide. Activates Beclin1 by competing against its negative regulator GAPR-1/GLIPR2.

包装规格：10 MG

产品编号：4083497

纯度规格：A cell-permeable inhibitor of mitochondrial branched-chain α-ketoacid dehydrogenase complex (BCKDC) regulatory kinase BDK (IC₅₀ = 6.3 μM).

包装规格：10 MG

产品编号：4083494

包装规格：50 MG

产品编号：4083491

包装规格：5 MG

产品编号：4083487

包装规格：25 MG

产品编号：4083485

包装规格：5 EA

产品编号：4083484

包装规格：5 EA

产品编号：4083483

包装规格：5 EA